Почечно-клеточный рак у пациентов, находящихся на диализе

Автор: Isao Ishikawa

Журнал: Злокачественные опухоли @malignanttumors

Статья в выпуске: 1 т.1, 2011 года.

Бесплатный доступ

Заболеваемость почечно-клеточным раком (ПКР) у пациентов, находящихся на диализе, выше, чем в общей популяции. Чем дольше больной получает гемодиализ, тем выше заболеваемость ПКР. Риск развития ПКР связан с формированием поликистоза почек. Некоторые виды ПКР у пациентов, находящихся на гемодиализе, или пациентов с заболеваниями почек поздних стадий не соответствуют гистологической классификации ПКР, представленной Всемирной Организацией Здравоохранения. Такие опухоли отличаются от спорадических; их называют ПКР, ассоциированным с приобретенным поликистозом почек (ППКП), или светлоклеточным-папиллярным ПКР у пациентов с заболеваниями почек поздних стадий. Рак почки на фоне ППКП развивается у пациентов, которые получают диализ длительно (более 10 лет). В связи с высокой заболеваемостью и отсутствием симптомов, пациентов находящихся на диализе из группы высокого риска, необходимо обследовать на предмет ПКР. Такой скрининг особенно важен для пациентов на диализе продолжительностью более 10 лет, пациентам с тяжелым ППКП и кандидатам на трансплантацию почки. Опухоль в почке, прилежащая к множественным приобретенным кистам, как правило, мало или совсем не накапливает контрастное вещество при КТ, а также не выступает за контур почки. Таким образом, дооперационная оценка ПКР у пациентов на длительном диализе затруднительна.

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Приобретенные кисты почек, гемодиализ, почечно-клеточный рак, пкр на фоне ппкп, ультразвуковое исследование с контрастированием с использованием перфторбутановых микропузырь- ков, пэт-кт, кт

Короткий адрес: https://sciup.org/14045401

IDR: 14045401

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