The pitfalls of direct oral anticoagulants

Anticoagulant drugs have undergone drastic changes in recent decades. The introduction of direct oral anticoagulants into clinical practice has led to their widespread use for long-term oral anticoagulant therapy. There is less control over therapy, and medications are prescribed by doctors of many specialties. This monitoring system for patients receiving direct oral anticoagulants is suboptimal. And the lack of antidotes for apixaban and rivaroxaban exacerbate the problem.