Penile hemodynamics with intracavenosal injection of alprostadil before and after the course of perineal muscles strengthening exercises

Introduction. Impact of perineal muscles strengthening exercises on penile hemodynamics in patients with erectile disfunction (ED) was studied. Materials and methods. Complete physical examination of patients was performed, including examination by a therapist, urologist, including medical tests and instrumental methods of examination. Patients with psychogenic erectile disfunction were excluded. The study engaged 24 men with the mean age 47,7±2,5 years ranging from 22 to 74 years, with a duration of ED of 19±2,9 months and scores on IIEF-5 scale 16,4±0,8. All patients gave written informed consent. In all patients power in perineal muscles was measured and Doppler sonography during pharmacologically induced erection was performed after intracavernosal injection of alprostadil (10 μg). Blood flow parameters in cavernosal and dorsal arteries and in deep dorsal vein in all phases of erection (flaccid state, tumescence, full erection) were measured. In fully erect state rigidity of the penis was evaluated. All patients underwent a course of perineal muscles strengthening exercises. After this training power in perineal muscles was measured and Doppler sonography during pharmacologically induced erection was performed again. Results. After perineal strengthening exercises power in perineal muscles increased on average in 3,4 times (p function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }