Gender differences in clinical and radiological parameters in patients with relapsing-remitting type of multiple sclerosis in the Kursk Region

Introduction. Multiple sclerosis (MS) is characterized by its course in patients of different genders. The described neurodegenerative and proinflammatory phenotypes of MS have different representation in men and women. The diversity of views on the influence of the location, size of demyelination foci and the degree of disability in patients with multiple sclerosis determines the importance of assessing these parameters by gender.The aim of the study was to analyze gender characteristics in the location of demyelination zones, the relationship between morphological and quantitative features of focal changes and disability in patients with multiple sclerosis.Materials and methods. A prospective analysis of magnetic resonance imaging data was performed in 103 patients (women - 54, men - 49; average age - 39±11.7) with relapsing-remitting multiple sclerosis during the period of persistent remission, who received outpatient care at the Kursk Regional Multidisciplinary Clinical Hospital in 2017-2024 using the consent criteria and correlation analysis.Results. The presence of periventricular foci of demyelination in 72.2% of cases was recorded in women, while in men this figure was 97.9%, the differences are significant (p function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }