Manufacturing of antiseptic films by electrospinning

Nanotechnology is a current trend in the development of new materials with unique properties for use in various fields of human activity. This article focuses on the development of antiseptic dressings containing new antibacterial components by electrospinning technique. To achieve the stated goal, this study required addressing the following tasks: selecting fiber-forming polymers and functional additives for producing nanofibrous antiseptic materials, determining electrospinning conditions using antibacterial additives, identifying the effect of antibacterial additives on the stability of the electrospinning process and the structure of the resulting materials, and evaluating the antibacterial activity of the nanofibrous samples with the addition of antibacterial additives. To ensure an antiseptic effect, it was proposed to use antibacterial additives such as tetramethylene diethylenetetramine and polyhexamethylene guanidine hydrochloride. The nanofibrous materials was obtaining using a Fluidnatek LE-50 machine. Polyvinyl alcohol was selected as the fiber-forming polymer. The study revealed that the use of offered functional additives can impart antibacterial properties to the material. It was observed that the obtained samples of nanofibrous materials possess sufficient antibacterial activity to reliably suppress the growth of pathogenic microorganisms under laboratory conditions.