Production of methoxyacetophenon by anyzole acylation

In the current work, the reaction of acylation of anisole with acetic anhydride is studied in order to obtain biologically active substances-p-methoxyacetophenone and m-methoxyacetophenone using aluminum, iron, cobalt chloride catalysts, as well as zeolite-based catalysts, cobalt-containing catalysts based on alumina and silica.