Popova M.I., Stolyarov S.A., Badeyan V.A. Carboxy-lymphotropic therapy in treatment of surgical soft tissue infections of lower extremities

Introduction. So far, surgical soft tissue infection accounts for more than half of all cases seeking specialized medical attendance, and its treatment is sometimes rather difficult. The purpose of the work is to study the results of carboxy-lymphotropic therapy while treating patients with surgical soft tissue infection of the lower extremities. Materials and Methods. The study enrolled 57 patients with manifestations of surgical soft tissue infection of the lower extremities. Criteria for enrollment: patients aged 18 to 75, lack of decompensation for concomitant somatic diseases, and lack of systemic inflammatory response. Withdrawal criteria: patients with diabetes mellitus, cancer, decompensation for concomitant somatic diseases, immunodeficiency states (HIV infection, primary immunodeficiency), injecting drug use, pregnancy and lactation. All patients were divided into two groups: the main group and the control group. The main group included 29 patients who underwent carboxy-lymphotropic therapy. Patients of the control group (n=28) were treated according to the standard protocol. Patients of both groups were examined identically. The examination included the study of the wound fluid pH, bacteriological examination of the wound fluid with antibiotic sensitivity test, cytological screening and the study of the microcirculation in the affected area with a laser analyzer «LAKK - M». Results. Carboxy-lymphotropic therapy as the main treatment method allowed to reduce the duration of patients' treatment and to accelerate the phase change in the wound process. It was proven both experimentally and clinically. Conclusion. Carboxy-lymphotropic therapy significantly improves treatment outcomes in patients with surgical soft tissue infection of the lower extremities. For patients with microcirculation disorders in the affected area, the described method should be mandatory.