Potential role of nutrients in immune boosting and aiding against COVID- 19 pathogenesis

Автор: Karki Kanchan, Bhandari Lakshika

Журнал: Журнал стресс-физиологии и биохимии @jspb

Статья в выпуске: 3 т.18, 2022 года.

Бесплатный доступ

COVID-19 or the novel Corona Virus is highly contagious and acute disease and is caused by Severe Acute Respiratory Syndrome Coronavirus-2 or SARS-CoV-2. The pathogenesis of Corona Virus is very complex and involves the suppression of host innate and antiviral immune response, cytokine storm is described as induction of oxidative stress followed by hyper inflammation which causes tissue fibrosis, pneumonia and lung injury. Several neutraceuticals have proven their abilities against viral pathogenesis and boosting immunity. These neutraceuticals involves Vitamin C, Vitamin D, Zinc, Selenium, and Copper. To boost immunity, combination of some of the phytonutrients may be used as food supplements. It may also help provide therapeutic assistance against COVID-19, preventing spread of virus and suppression of hyper inflammation. This review speculates the significance of nutrition as a mitigation strategy to support immune function amid the COVID-19 pandemic, identifying food groups and key nutrients of importance that may affect the outcomes of respiratory infections. To survive in the current conditions of COVID-19 it is necessary to build up the immunity. An appropriate diet can make sure that a body is capable against the viral pathogenesis.

Еще

Covid-19, neutraceuticals, vitamin c, vitamin d, zinc, selenium, copper

Короткий адрес: https://sciup.org/143179056

IDR: 143179056

Список литературы Potential role of nutrients in immune boosting and aiding against COVID- 19 pathogenesis

  • Aglipay M, Birken CS, Parkin PC, et al. (2017) Effect of High-Dose vs Standard-Dose Wintertime Vitamin D Supplementation on Viral Upper Respiratory Tract Infections in Young Healthy Children. JAMA: The Journal of the American Medical Association. 318(3):245-254.
  • Asdamongkol N, Phanachet P, Sungkanuparph S (2013)Low plasma zinc levels and immunological responses to zinc supplementation in HIV-infected patients with immunological discordance after antiretroviral therapy. Japanese Journal of Infectious Diseases. 66:469-474. Baez-Santos Y, St John E, Mesecar A (2015) The compounds. Antiviral Research. 115:21-38.
  • Basnet S, Shrestha P, Sharma A, Mathisen M, Prasai R, Bhandari N (2012)A randomized controlled trial of zinc as adjuvant therapy for severe pneumonia in young children. Pediatrics. 129:701-708.
  • Brautigan D, Bornstein P, Gallis B. (1981) Phosphotyrosyl-protein phosphatase. Specific inhibition by Zn2+. The Journal of Biological Chemistry. 256:6519-6522
  • Chambers A, Krewski D, Birkett N, Plunkett L, Hertzberg R, Danzeisen R. (2010) An exposure-response curve for copper excess and deficiency. Journal of Toxicology and Environmental Health, Part B: Critical Reviews. 13:546-578.
  • Cinatl, J., Cinatl, J., Weber, B., Rabenau, H., Gümbel, H. O., Chenot, J. F..... & Doerr, H. W. (1995). In vitro inhibition of human cytomegalovirus replication in human foreskin fibroblasts and endothelial cells by ascorbic acid 2-phosphate. Antiviral research, 27(4), 405-418.
  • Cullinan S, Diehl J. (2004) PERK-dependent Activation of Nrf2 Contributes to Redox Homeostasis and Cell Survival following Endoplasmic Reticulum Stress. The Journal of Biological Chemistry. 279:2010820117.
  • De la FuenteM, Ferrandez M, Burgos M, Soler A, Prieto A, Miquel J (1998)Immune function in aged women is improved by ingestion of vitamins C and E. The Canadian Journal of Physiology and Pharmacology. 76(4):373-380.
  • Derouiche S (2020) Oxidative stress associated with SARS- Cov-2 (COVID-19) Increase the Severity of the Lung Disease -A Systematic Review. Journal of Infectious Diseases and Epidemiology. 6:121.
  • Dikalov S, Nazarewicz R (2013) Angiotensin II-Induced Production of Mitochondrial Reactive Oxygen Species: Potential Mechanisms and Relevance for Cardiovascular Disease. Antioxidants & Redox Signalling. 19:1085-1094.
  • Gamble A, William B (2020) Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1N. The New England Journal of Medicine. 382:1564-1567.
  • Gan R, Rosoman N, Henshaw D, Noble E, Georgius P, Sommerfeld N (2020) COVID-19 as a viral functional ACE2 deficiency disorder with ACE2 related multi-organ disease. Medical Hypotheses. 144:110024.
  • Ganguly A, Chakraborty S, Datta K, Hazra A, Datta S,Chakraborty J (2011) A randomized controlled trial of oral zinc in acute pneumonia in children aged between 2 months to 5 years. The Indian Journal of Pediatrics. 78:1085-1090.
  • Gombart A, Pierre A, Maggini S (2020) A review of micronutrients and the immune system-working in harmony to reduce the risk of infection. Nutrients. 12:236.
  • Han Y, Chang G, Juo C, Lee H, Yeh S, Hsu J (2005) Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): expression, purification, characterization, and inhibition. Biochemistry. 44:10349-10359.
  • Hoffmann M, Kleine-Weber H, Schroeder S, Krüger N, Herrler T, Erichsen S (2020) SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 181(2):271-280.
  • Holick M (2007) Vitamin D deficiency. The New England
  • Journal of Medicine. 357:266-281.
  • Hunt C, Chakravorty N, Annan G, Habibzadeh N, Schorah C (1994) The clinical effects of vitamin C supplementation in elderly hospitalised patients with acute respiratory infections. The International Journal for Vitamin and Nutrition Research.
  • Mastroianni C, Severino P (2020) Diet Supplementation, probiotics, and nutraceuticals in SARS-CoV-2 infection: a scoping review. Nutrients. 12(6):1718.
  • Jariwalla R, Roomi M, Gangapurkar B, Kalinovsky T, Niedzwiecki A, Rath M (2007)Suppression of influenza A virus nuclear antigen production and neuraminidase activity by a nutrient mixture containing ascorbic acid, green tea extract and amino acids. Biofactors. 31(1):1-15.
  • Jayachandran M, Rani P, Arivazhagan P, Panneerselvam C (2000) Neutrophil phagocytic function and humoral immune response with reference to ascorbate supplementation in aging humans. Journal of Anti-Aging Medicine. 3(1):37-42.
  • Jolliffe, D. A., Stefanidis, C., Wang, Z., Kermani, N. Z., Dimitrov, V., White, J. H..... & Martineau, A. R. (2020). Vitamin D metabolism is dysregulated in asthma and chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine, 202(3), 371-382.
  • KelleyD, Daudu P, Taylor P, Mackey B, Turnlund J (1995) Effects of low-copper diets on human immune response. The American Journal of Clinical Nutrition. 62(2):412-416.
  • Laird E, Rhodes J, Kenny R (2020) Vitamin D and Inflammation: Potential Implications for Severity of Covid-19. The Irish Medical Journal. 113(5):81.
  • Li X, Geng M, Peng Y, Meng L, Lu S (2020) Molecular immune pathogenesis and diagnosis of COVID-19. Journal of Pharmaceutical Analysis. 10:102-108.
  • McCartney D, Byrne D (2020) Optimisation of Vitamin D status for enhanced immuno-protection against Covid-19. The Irish Medical Journal. 113(4):58.
  • Merad, M., & Martin, J. C. (2020). Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages. Nature reviews immunology, 20(6), 355-362.
  • Meydani S, Meydani M, Jeffrey B, Lynette L, Pedrosa M, Diamond R, Schaefer E (2020) Assessment of the safety of supplementation with different amounts of vitamin E in healthy older adults. The American Journal of Clinical Nutrition. 68(2):311-318.
  • Galley H (2011) Oxidative stress and mitochondrial
  • Hemilä H, Chalker E (2013) Vitamin C for preventing 64(3):212-219.
  • Infusino F, Marazzato M, Mancone M, Fedele F, Moriguchi S, Muraga M (2000) Vitamin E and immunity. Vitamins & Hormones. 59:305-336.
  • Oxidative Stress in Sepsis. Acute and Critical Care. 33:65-72.
  • Nelson H, Qiujun S, Dael P, Schiffrin E (2001) Host nutritional selenium status as a driving force for influenza virus mutations The FASEB Journal. 15(10):1846-1848.
  • Oudit G, Kassiri Z, Patel M, Chappell M, Butany J, Backx P, Tsushima R, Scholey J, Khokha R, Penninger J (2007) Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice. Cardiovascular Research. 75:29-39.
  • Overbeck S, Rink L, Haase H (2008) Modulating the immune response by oral zinc supplementation: a single approach for multiple diseases. Archivum immunologiae et therapiae experimentalis. 56:1530.
  • Pike J, Christakos S (2017) Biology and Mechanisms of Action of the Vitamin D Hormone. Endocrinology and Metabolism Clinics. 46:815-843.
  • Pathophysiological implications justifying antioxidant co-therapy. Burns. 43:471-485.
  • Rincón J, Correia D, Arcaya J, Finol E, Fernández A, Pérez M, Yaguas K,Talavera E, Chávez M, Summer R (2015) Role of Angiotensin II type 1 receptor on renal NAD(P)H oxidase, oxidative stress and inflammation in nitric oxide inhibition induced-hypertension. Life Sciences. 124:81-90.
  • Rondanelli M, Miccono A, Lamburghini S, Avanzato I, Riva A, Allegrini P, Faliva M, Peroni G, Nichetti M, Perna S (2018) Self-Care for Common Colds: The Pivotal Role of Vitamin D, Vitamin C, Zinc, and Echinacea in Three Main Immune Interactive Clusters (Physical Barriers, Innate and Adaptive Immunity) Involved during an Episode of Common Colds-Practical Advice on Dosages and on the Time to Take These Nutrients/Botanicals in order to Prevent or Treat Common Colds. Evidence-Based Complementary and Alternative Medicine.
  • Rondanelli M., Miccono A., Lamburghini S., Avanzato I., Riva A., Allegrini P., Faliva M., Peroni G., Nichetti M. and Perna S (2018). Self-Care for Common Colds: The Pivotal Role of Vitamin D, Vitamin C, Zinc, and Echinacea in Three Main Immune Interactive Clusters (Physical Barriers, Innate and Adaptive Immunity) Involved during an Episode of Common Colds-Practical Advice on Dosages and on the Time to Take These Nutrients/Botanicals in order to Prevent or Treat Common Colds. Evidence-Based Complementary and Alternative Medicine. 2018:5813095.
  • Sagripanti J, Routson L, Lytle C (1993) Virus inactivation by copper or iron ions alone and in the presence of peroxide. Applied and Environmental Microbiology. 59:4374-4376.
  • Sawalha A, Zhao M, Coit P, Lu Q (2020) Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients. Clinical Immunology. 215:108410.
  • Sawalha A., Zhao M., Coit P. and Lu Q (2020). Epigenetic dysregulation of ACE2 and interferonregulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients. Clinical Immunology. 215:108410.
  • Schiavon, M., Nardi, S., Dalla Vecchia, F., & Ertani, A. (2020). Selenium biofortification in the 21st century: Status and challenges for healthy human nutrition. Plant and Soil, 453(1), 245-270.
  • Schoggins J, Wilson S, Panis M (2011) A diverse range of gene products are effectors of the type I interferon antiviral response. Nature. 472:481-485.
  • Semba, R. D., & Tang, A. M. (1999). Micronutrients and the pathogenesis of human immunodeficiency virus infection. British Journal of Nutrition, 81(3), 181189.
  • Sharifi A, Vahedi H, Nedjat S, Rafiei H, Hosseinzadeh-Attar M (2019) Effect of single-dose injection of vitamin D on immune cytokines in ulcerative colitis patients: a randomized placebo-controlled trial. APMIS. 127:681-687.
  • Shilotri P, Bhat K (1977) Effect of mega doses of vitamin C on bactericidal activity of leukocytes. The American Journal of Clinical Nutrition. 30(7):1077-1081.
  • Traber M (2007) Vitamin E regulatory mechanisms. The Annual Review of Nutrition. 27:347-362.
  • Traber M. and Atkinson J (2007). Vitamin E, antioxidant and nothing m more. Free Radical Biology and Medicine. 43:4-15.
  • Wang J, Zhang R, Bai J (2020) An anti-oxidative therapy for ameliorating cardiac injuries of critically ill COVID-19-infected patients. The International Journal of Cardiology. 312:137-138.
  • Wei Y, Sowers J, Nistala R, Gong H Uptergrove G, Clark S, Morris E, Szary N. Manrique C, Stump C (2006) Angiotensin II-induced NADPH Oxidase Activation Impairs Insulin Signaling in Skeletal Muscle Cells. The Journal of Biological Chemistry. 281:35137-35146.
  • Zablocki D, Sadoshima J (2013) Angiotensin II and Oxidative Stress in the Failing Heart. Antioxidants & Redox Signaling. 2013.19:1095-1109.
  • Zingg J (2015). Vitamin E: A role in signal transduction. The Annual Review of Nutrition. 35:135-173.
Еще
Статья обзорная