Role of repeat staging laparoscopy in locoregionally advanced gastric or gastroesophageal cancer after neoadjuvant therapy

Background: Nowadays there are no international recommendations regarding the necessity of repeated diagnostic laparoscopy (with cytological examination or without it) after preoperative chemotherapy for resectable gastric cancer Purpose: To determine the indications for the repeated laparoscopic surgery in gastric or gastroesophageal cancer patientsMaterials and methods: The information on 449 IB-III stage gastric cancer patients was analyzed. After 4 cycles of chemotherapy 52 patients underwent diagnostic laparoscopy with peritoneal fluid cytology testing.Results: The multifactorial analysis showed that tumor progression detected on CT scans and gastroscopy, subtotal gastric involvement (p Results: The repeat staging laparoscopy after neoadjuvant chemotherapy is safe and may be considered for a certain category of patients.