Increasing nonspecific stability of service dogs

A biopreparation Dog-Stim-N-B was developed and a scientific and practical justification was given for its feasibility in the canine center for raising dogs of the German shepherd breed. Selective mobilization of morphological and biochemical profiles of blood, cellular and humoral factors of nonspecific resistance of dog organism is established against the background of intramuscular injection of first-tested biopreparation Dog-Stim-N-B and previously tested Prevention-N-E. The biologics used in the experiments showed a wide range of bio-effects: activated the production of red blood cells and increased the concentration of hemoglobin in the blood of dogs, that is, improved hematopoiesis, but did not have a stimulating effect on the production of white blood cells; caused physiological eosinophilia, moderate neutrophylopenia with neutrophilic nucleus shift to the right and lymphocytosis; increased protein metabolism, mainly due to synthesis of albumin and y-globulin fractions; activated cellular and humoral factors of nonspecific resistance of the organism.