Increasing stress resistance by transcranial electrical stimulation in patients after prostate cancer surgery

Anxiety in men often increases during the rehabilitation period after prostate cancer surgery. Moreover, simultaneous development of erectile dysfunction is also observed. This contributes to psycho-emotional stress formation. The aim of the study is to evaluate the effect of transcranial electrical stimulation (tES) on stress vulnerability during the rehabilitation period after various types of prostate cancer surgery. Materials and Methods. The authors estimated anxiety level and erectile dysfunction in 124 men 6 months after prostate cancer surgery. The patients were divided into groups according to the surgery type: Group 1 (n=24) - high-intensity focused ultrasound (HIFU); Group 2 (n=50) - laparoscopic radical prostatectomy; Group 3 (n=50) - laparotomic radical prostatectomy. Serum concentration of adrenocorticotropic hormone (ACTH), cortisol, adrenaline, interleukins 1 and interleukins 2 (IL-1, IL-2) and stress vulnerability level according to N.V. Kirsheva and N.V. Ryabchikova test, Holmes and Rahe stress scale, S. Cohen and G. Williamson test, and “Prognosis" method was determined twice: before and after tES. Results. Erectile dysfunction was detected in 37 patients 6 months after radical prostatectomy (Group 2, n=17; Group 3, n=20). All the patients of Group 1 (HIFU) restored erection. A decrease in stress vulnerability was observed in all patients, regardless of the surgery type and the severity of functional disorders. After tES, a significant decrease in the levels of ACTH, cortisol, IL-1, IL-2 was estimated (p function show_eabstract() { $('#eabstract1').hide(); $('#eabstract2').show(); $('#eabstract_expand').hide(); }