Predictors of local recurrence of renal cell cancer. Our experience

Автор: Gaas M.Y., Kaprin A.D., Vorobyev N.V., Kalpinsky A.S., Kozlov V.V., Inozemtsev R.O.

Журнал: Сибирский онкологический журнал @siboncoj

Рубрика: Клинические исследования

Статья в выпуске: 4 т.21, 2022 года.

Бесплатный доступ

Risk factors for renal cell cancer (Rcc) recurrence, including its local form, include stage and high Fuhrman grading system score, regional lymph node involvement, microvascular invasion, tumor necrosis, positive surgical margin, and sarcomatoid or rhabdoid tumor differentiation. Objective. the study analyzes data from moscow Research oncological institute named by pa Herzen to determine the predictors of local recurrence of kidney cancer based on the data from surgically treated patients with local recurrent Rcc. material and methods. We analyzed retrospectively data from 87 patients who were divided into 2 groups: 1-st, patients with detected local recurrence of kidney cancer (n=43), and 2-nd, control group (n=44). the following predictors were evaluated: tumor size, tumor histotype, tumor stage, Fuhrman grading system, surgical margin status, tumor necrosis, sarcomatoid and rhabdoid changes, microvascular invasion, hemorrhage and invasion of collecting system components (css), renal capsule, and perirenal cellular tissue and primary treatment. Results. the risk of local recurrence was higher in the primary tumor, over 40 mm in diameter (oR=5.8, p function show_abstract() { $('#abstract1').hide(); $('#abstract2').show(); $('#abstract_expand').hide(); }

Еще

Renal cell carcinoma, local recurrence, predictors of local recurrence, risk factors of local recurrence, prognostic factors of local recurrence, predisposing factors of local recurrence, local recurrence-free survival rate

Короткий адрес: https://sciup.org/140295746

IDR: 140295746   |   DOI: 10.21294/1814-4861-2022-21-4-16-24

Список литературы Predictors of local recurrence of renal cell cancer. Our experience

  • Shuch B.M., Lam J.S., Belldegrun A.S., Figlin R.A. Prognostic factors in renal cell carcinoma. Semin Oncol. 2006; 33(5): 563-75. doi: 10.1053/j.seminoncol.2006.06.006.
  • NguyenD.P., VertosickE.A., CorradiR.B., Vilaseca A., BenfanteN.E., Touijer K.A., Sjoberg D.D., Russo P. Histological subtype of renal cell carcinoma significantly affects survival in the era of partial nephrectomy. Urol Oncol. 2016; 34(6). doi: 10.1016/j.urolonc.2016.01.005.
  • Patard J.J., LerayE., Rioux-LeclercqN., CindoloL., Ficarra V., Zis-man A., De La Taille A., Tostain J., Artibani W., Abbou C.C., Lobel B., Guillé F., Chopin D.K., Mulders P.F., Wood C.G., Swanson D.A., Figlin R.A., Belldegrun A.S., Pantuck A.J. Prognostic value of histologic subtypes in renal cell carcinoma: a multicenter experience. J Clin Oncol. 2005; 23(12): 2763-71. doi: 10.1200/JC0.2005.07.055.
  • Leibovich B.C., Lohse C.M., Crispen P.L., Boorjian S.A., Thompson R.H.,BluteM.L., Cheville J.C. Histological subtype is an independent predictor of outcome for patients with renal cell carcinoma. J Urol. 2010; 183(4): 1309-15. doi: 10.1016/j.juro.2009.12.035.
  • Wood E.L., Adibi M., Qiao W., Brandt J., Zhang M., Tamboli P., Matin S.F., WoodC.G., Karam J.A. Local Tumor Bed Recurrence Following Partial Nephrectomy in Patients with Small Renal Masses. J Urol. 2018; 199(2): 393-400. doi: 10.1016/j.juro.2017.09.072.
  • Kriegmair M.C., Bertolo R., Karakiewicz P.I., Leibovich B.C., Ljungberg B., Mir M.C., Ouzaid I., Salagierski M., Staehler M., van Poppel H., Wood C.C., Capitanio U.; Young Academic Urologists Kidney Cancer working group ofthe European Association of Urology. Systematic Review of the Management of Local Kidney Cancer Relapse. Eur Urol Oncol. 2018; 1(6): 512-23. doi: 10.1016/j.euo.2018.06.007.
  • Margulis V., McDonaldM., Tamboli P., Swanson D.A., Wood C.G. Predictors of oncological outcome after resection of locally recurrent renal cell carcinoma. J Urol. 2009; 181(5): 2044-51. doi: 10.1016/j. juro.2009.01.043.
  • Barbas Bernardos G., Herranz Amo F., Caño Velasco J., Cancho Gil M.J., Mayor de Castro J., Aragón Chamizo J., Polanco Pujol L., Hernández Fernández C. Influence of venous tumour extension on local and remote recurrence of stage pT3a pN0 cM0 kidney tumours. Actas Urol Esp (Engl Ed). 2019; 43(2): 77-83. doi: 10.1016/j.acuro.2018.06.007.
  • Crispen P.L., Boorjian S.A., Lohse C.M., Sebo T.S., Cheville J.C., Blute M.L., Leibovich B.C. Outcomes following partial nephrectomy by tumor size. J Urol. 2008; 180(5): 1912-7. doi: 10.1016/j.juro.2008.07.047.
  • Andrews J.R., Atwell T., Schmit G., Lohse C.M., Kurup A.N., Weisbrod A., Callstrom M.R., Cheville J.C., Boorjian S.A., Leibovich B.C., Thompson R.H. Oncologic Outcomes Following Partial Nephrectomy and Percutaneous Ablation for cT1 Renal Masses. Eur Urol. 2019; 76(2): 244-51. doi: 10.1016/j.eururo.2019.04.026.
  • Minervini A., Campi R., Sessa F., Derweesh I., Kaouk J.H., Mari A., Rha K.H., Sessa M., Volpe A., Carini M., Uzzo R.G. Positive surgical margins and local recurrence after simple enucleation and standard partial nephrectomy for malignant renal tumors: systematic review of the literature and meta-analysis of prevalence. Minerva Urol Nefrol. 2017; 69(6): 523-38. doi: 10.23736/S0393-2249.17.02864-8.
  • Bernhard J.C., Pantuck A.J., WallerandH., CrepelM., Ferriere J.M., BellecL., Maurice-Tison S., Robert G., Albouy B., Pasticier G., SoulieM., Lopes D., LacroixB., Bensalah K., Pfister C., ThuretR., Tostain J., De La TailleA., SalomonL., Abbou C., ColombelM., BelldegrunA.S., Patard J.J. Predictive factors for ipsilateral recurrence after nephron-sparing surgery in renal cell carcinoma. Eur Urol. 2010; 57(6): 1080-6. doi: 10.1016/j. eururo.2010.02.019.
  • Shah P.H., Moreira D.M., Okhunov Z., Patel V.R., Chopra S., RazmariaA.A., AlomM., GeorgeA.K., Yaskiv O., SchwartzM.J., DesaiM., ViraM.A., Richstone L., Landman J., Shalhav A.L., Gill I., Kavoussi L.R. Positive Surgical Margins Increase Risk of Recurrence after Partial Nephrectomy for High Risk Renal Tumors. J Urol. 2016; 196(2): 327-34. doi: 10.1016/j.juro.2016.02.075.
  • 14.MarchinenaP.G., TirapeguiS., GonzalezI.T., Jurado A., Gueglio G. Positive surgical margins are predictors of local recurrence in conservative kidney surgery for pT1 tumors. Int Braz J Urol. 2018; 44(3): 475-82. doi: 10.1590/S1677-5538.IBJU.2017.0039.
  • Abu-Ghanem Y., Ramon J., Berger R., Kaver I., Fridman E., Leiboowitz-Amit R., Dotan Z.A. Positive surgical margin following radical nephrectomy is an independent predictor of local recurrence and disease-specific survival. World J Surg Onc 15. 2017. doi: 10.1186/ s12957-017-1257-6.
  • BertoloR., NicolasM., Garisto J., Magi-Galluzzi C., McKenney J.K., Kaouk J. Low Rate of Cancer Events After Partial Nephrectomy for Renal Cell Carcinoma: Clinicopathologic Analysis of 1994 Cases with Emphasis on Definition of «Recurrence». Clin Genitourin Cancer. 2019; 17(3): 209-215. doi: 10.1016/j.clgc.2019.03.004.
  • Chen X.S., Zhang Z.T., Du J., Bi X.C., Sun G., Yao X. Optimal surgical margin in nephron-sparing surgery for T1b renal cell carcinoma. Urology. 2012; 79(4): 836-9. doi: 10.1016/j.urology.2011.11.023.
  • Oh J.J., Byun S.S., Lee S.E., Hong S.K., Lee E.S., Kim H.H., Kwak C., Ku J.H., Jeong C.W., Kim Y.J., Kang S.H., Hong S.H. Partial nephrectomy versus radical nephrectomy for non-metastatic pathological T3a renal cell carcinoma: a multi-institutional comparative analysis. Int J Urol. 2014; 21(4): 352-7. doi: 10.1111/iju.12283.
  • CorreaA.F., Jegede O., HaasN.B., FlahertyK.T., PinsM.R., Messing E.M., Manola J., Wood C.G., Kane C.J., JewettM.A.S., Dutcher J.P., DiPaolaR.S., CarducciM.A., UzzoR.G. Predicting Renal Cancer Recurrence: Defining Limitations of Existing Prognostic Models With Prospective Trial-Based Validation. J Clin Oncol. 2019; 37(23): 2062-71. doi: 10.1200/JC0.19.00107.
Еще
Статья научная