Laser Doppler flowmetry as technique estimating regulatory mechanisms of skin microcirculation in patients with uterine fibroid in early post-embolization period

A complex of various symptoms called postembolization syndrome (PS) can develop during the early postoperative period after uterine artery embolization (UAE) while treating uterine fibroid. It is still very importatnt to analyze PS origin, development and ways of correction depending on its severity. The aim of the study was to assess the regulatory microcirculation mechanisms in PS development. Materials and Methods. The authors devided 81 patients into 3 groups depending on the PS severity: mild case (n=36) - Group 1, moderate case (n=30) - Group 2, severe case (n=15) - Group 3. Indicators of rhythmic blood flow fluctuations were recorded during the occlusive test before and after UAE by means of laser Doppler flowmetry. Frequency-amplitude spectrum of perfusion oscillations was calculated by means of wavelet transforms. It was composed of active microcirculation mechanisms (endothelial, neurogenic, and myogenic) and passive regulation factors (respiratory, and cardiac)...