The use of linezolid and bedaquiline in patients with pulmonary tuberculosis in the postoperative period

Objective: to study the effectiveness of multidrug- and pre-extensively drug-resistant tuberculosis (TB) chemotherapy regimens with the inclusion of linezolid (Lzd) and bedaquiline (Bq) in operated patients for pulmonary TB. Material and methods. A non-randomized continuous single-center retrospective study of the data of 154 patients operated for drug-resistant pulmonary tuberculosis in the period from 2018 to 2023 was performed. A comparative analysis of the effectiveness of chemotherapy regimens was carried out depending on the inclusion of new anti-tuberculosis drugs in it.