Sodium profiling and ultrafiltration in patients undergoing programmed hemodialysis: therapy optimization

The objective of the study is to evaluate the effect of sodium profiling and ultrafiltration on the clinical and functional status of patients undergoing programmed hemodialysis (HD). Materials and Methods. The study consisted of two stages. During the first stage, a group of patients (n=25) undergoing HD was formed. The follow-up period lasted 20 months. Evaluation of blood pressure levels, interdialytic weight gain and laboratory parameters was carried out taking into consideration five variants of sodium profiling and ultrafiltration. During the second stage a comparative analysis of patients' clinical and functional status according to the profiling option (3 and 5) was conducted in the group (n=20). Results. During the first stage, the authors found out that profiles 3 and 5 were desirable for blood pressure stabilization, interdialytic weight gain loss and improvement of laboratory parameters. The second stage showed that using profile 5 in case of adequate hemodialysis contributes to improving clinical and laboratory status and reducing concomitant drug therapy in 63.3% of patients. Conclusions. Under profiling patients undergoing hemodialysis demonstrate blood pressure stabilization, interdialytic weight gain loss and improvement in such blood values as total protein, albumin and hemoglobin.