Prediction of pregnancy outcomes in women with antiphospholipid syndrome depending on the gestation period

Antiphospholipid syndrome (AFS) is a systemic process that affects all organs and tissues and is determined by clinical and laboratory criteria. Currently established clinical manifestations of AFS affect two systems: vascular, causing thrombotic phenomena, and uteroplacental blood flow, which leads to pregnancy complications. At the same time, infectious diseases are still one of the main causes of perinatal losses worldwide. The clinical symptoms of TORCH infections remain poorly expressed, which causes certain difficulties in making a diagnosis and carrying out therapeutic measures. The consequences for the fetus and newborn vary from asymptomatic infection to sepsis, malformations and fetal death. Examination of pregnant women for the presence of infectious agents is an important part of the antenatal surveillance program. The relevance of studying TORCH infections in pregnant women is determined not only by significant perinatal losses, but also by the fact that a fetus who has had an infection often reveals a congenital pathology that leads to serious health disorders and disability.