World Health Organization program “Registry of acute myocardial infarction”: capabilities and prospects for studying and predicting outcomes of socially significant diseases

The article presents main results of 30-year-long activity of the WHO program “Registry of Acute Myocardial Infarction” (RAMI) in Tomsk. Characteristics of epidemiology, clinical course, outcomes, and long-term prognosis of acute myocardial infarction (AMI) were studied in the population including working-age patients. Mathematical model was developed to identify the group of patients with high risk for adverse cardiovascular events in the long-term period of myocardial infarction (MI). Apart from comprehensive studies of AMI, epidemiology of unstable angina (UA) was analyzed and unique data were generated regarding the prevalence rate, specific aspects of onset, and clinical course of this pathology both in general and for individual clinical forms. The use of RAMI data enabled to receive valuable information for practice and to develop practical recommendations for optimal ambulatory management of high- and very high-risk patients who suffered acute coronary event.