Аntitumor MRNA vaccines based on neoantigens

Автор: Starostina E.V., Nizolenko L.F., Karpenko L.I., Ilyichev A.A.

Журнал: Сибирский онкологический журнал @siboncoj

Рубрика: Обзоры

Статья в выпуске: 6 т.23, 2024 года.

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Objective: to summarize the available data on clinical trials of vaccines based on mRNA encoding neoantigens. Material and Methods. Data were searched on https://classic.clinicaltrials.gov and https://pubmed.ncbi.nlm. nih.gov/, from January 2013 to May 2024 using the keywords “neoantigen” and “vaccine”, and the information on mRNA-based drugs was then selected. Of the 148 studies retrieved, 54 were selected to write a systematic review.

Oncology, immunotherapy, mrna vaccines, neoantigens, clinical trials, review

Короткий адрес: https://sciup.org/140308730

IDR: 140308730   |   DOI: 10.21294/1814-4861-2024-23-6-149-158

Статья обзорная