Противораковые МРНК-вакцины на основе неоантигенов

Противораковые МРНК-вакцины на основе неоантигенов

Автор: Старостина Е.В., Низоленко Л.Ф., Карпенко Л.И., Ильичев А.А.

Журнал: Сибирский онкологический журнал @siboncoj

Рубрика: Обзоры

Статья в выпуске: 6 т.23, 2024 года.

Бесплатный доступ

Цель исследования - обобщение имеющихся данных о клинических испытаниях вакцин, основанных на мРНК, кодирующих неоантигены. материал и методы. Поиск опубликованных с января 2013 г. по май 2024 г. данных проводился на сайтах https://classic.clinicaltrials.gov и https://pubmed.ncbi.nlm.nih. gov/ по ключевым словам «neoantigen» и «vaccine», а затем отбиралась информация о препаратах на основе мРНК. Из 148 найденных исследований 54 было отобрано для написания систематического обзора.

Рак, иммунотерапия, мрнк-вакцины, неоантигены, клинические испытания, обзор

Короткий адрес: https://sciup.org/140308730

IDR: 140308730   |   DOI: 10.21294/1814-4861-2024-23-6-149-158

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