Antiviral agents. IV. Synthesis of 1- [4- (aryl) butyl] uracil derivatives
Автор: Babkov D.A., Paramonova M.P., Ozerov A.A., Novikov M.S.
Журнал: Волгоградский научно-медицинский журнал @bulletin-volgmed
Рубрика: Фармакология токсикология
Статья в выпуске: 3 (31), 2011 года.
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Novel 1-[4-(aryl)butyl]uracil derivatives were obtained via sylil-Hilbert-Johnson reaction between 2,4-bis(trimethylsyliloxy)pyrimidine and corresponding 4-(aryl)butyl bromides with the purpose of investigating the synthetic approach to new potent non-nucleoside HIV-1 reverse trascriptase inhibitors. Target compounds were characterized by their physico-chemical and spectral properties.
Synthesis, uracil, 4-bis(trimethylsilyloxy)pyrimidine, potential antiviral agents
Короткий адрес: https://sciup.org/142148907
IDR: 142148907
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