Purinergical regulation of synaptic transfer in phase and tonic muscles of vertebrates

Автор: Grishin S.N., Morozov O.G., Anfinogentov V.I., Kamaliev R.R., Morozov G.A., Ziganshin A.U.

Журнал: Известия Самарского научного центра Российской академии наук @izvestiya-ssc

Рубрика: Биотехнологии и биоинженерия

Статья в выпуске: 4-3 т.12, 2010 года.

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By means of the computer software package «Mathcad Professional 2000» modeling of purine action - АТP and its final derivative adenosine on amplitude of post-synaptic answers in nervously-muscular transitions of phase and tonic muscles in a lake frog was spent. It is known, that АТP, as well as adeno-sine, by a principle of negative feedback oppresses the quantum emission in synaptic gap. In synapses of tonic musculation АТP, unlike the adenosine keeping the effect, causes rising amplitude of post-synaptic answers. The system of the kinetic equations was solved by Runge-Kuttа method with the fixed step. Resulting curves of mathematical modeling in general repeat experimental data. Concrete value of poly-nom coefficients and value of equilibrium constants have been received.

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Adenosine, phase and tonic muscles, mathematical modeling, атp

Короткий адрес: https://sciup.org/148199462

IDR: 148199462

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