Purine metabolism and microalbuminuria in patients with metabolic syndrome

The aim of this work was to study the state of purine metabolism and microalbuminuria in patients with metabolic syndrome. We examined 50 patients aged 30-55 years, who were randomized into 3 groups: I (control) - healthy individuals t - 15 people, II - patients with arterial hypertension - 18 people, group III - patients with arterial hypertension in combination with metabolic syndrome - 32 people. The results of the studies showed that the concentration of UA in the blood significantly correlated with the severity of obesity, hyperinsulinemia, triglyceridemia and glycemia - parameters that reflect the state of IR. Thus, the data obtained indicate that hyperuricemia is a metabolic disorder and one of the components inherent in the metabolic syndrome.