Рак вульвы. Вклад лучевой терапии в лечение заболевания

Рак вульвы. Вклад лучевой терапии в лечение заболевания

Автор: Лушникова П.А., Сухих Е.С., Старцева Ж.А.

Журнал: Сибирский онкологический журнал @siboncoj

Рубрика: Обзоры

Статья в выпуске: 3 т.23, 2024 года.

Бесплатный доступ

Цель исследования - анализ и обобщение имеющихся литературных данных о современных методах лучевой терапии рака вульвы, показаниях к радиотерапии (предоперационной, радикальной, послеоперационной), объемах облучения при различных стадиях заболевания, а также принципах лекарственной и сопроводительной терапии. материал и методы. В основу литературного обзора положены клинические рекомендации МЗ РФ и National Comprehensive Cancer Network (NCCN), а также проведен поиск источников в системах PubMed и cochrane Library. Включены литературные источники и публикации с 2005 по 2023 г.

Рак вульвы, сторожевой лимфатический узел, пахово-бедренная лимфаденэктомия, дистанционная лучевая терапия, брахитерапия, лекарственная радиомодификация

Короткий адрес: https://sciup.org/140305921

IDR: 140305921   |   DOI: 10.21294/1814-4861-2024-23-3-150-158

Список литературы Рак вульвы. Вклад лучевой терапии в лечение заболевания

  • Ashrafyan L.A, Antonova I.B., Berlev I.V., Verenikina E.V., Grinevich V.N., Demidova L.V., Kolomiets L.A., Kravets O.A., Kreinina Yu.M., Kuznetsov V.V., Kuznetsov V.V. Obshcherossiiskii natsional'nyi soyuz «Assotsiatsiya onkologov Rossii». Klinicheskie rekomendatsii po lecheniyu raka vul'vy. 2020.
  • Abu-Rustum N.R., Yashar C.M., Arend R., Barber E., Bradley K., Brooks R., Campos S.M., Chino J., Chon H.S., Crispens M.A., Damast S., Fisher C.M., Frederick P., Gaffney D.K., Gaillard S., Giuntoli R. II, Glaser S., Holmes J., Howitt B.E., Kendra K., Lea J., Lee N., MantiaSmaldone G., Mariani A., Mutch D., Nagel C., Nekhlyudov L., Podoll M., Rodabaugh K., Salani R., Schorge J., Siedel J., Sisodia R., Soliman P., Ueda S., Urban R., Wethington S.L., Wyse E., Zanotti K., McMillian N., Espinosa S. Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2024; 22(2): 117-35. https://doi.org/10.6004/jnccn.2024.0013.
  • Scampa M., Kalbermatten D.F., Oranges C.M. Squamous Cell Carcinoma of the Vulva: A Survival and Epidemiologic Study with Focus on Surgery and Radiotherapy. J Clin Med. 2022; 11(4): 1025. https://doi.org/10.3390/jcm11041025.
  • Siegel R.L., Miller K.D., Fuchs H.E., Jemal A. Cancer Statistics, 2021. CA Cancer J Clin. 2021; 71(1): 7-33. https://doi.org/10.3322/caac.21654. Erratum in: CA Cancer J Clin. 2021; 71(4): 359. https://doi.org/10.3322/caac.21669.
  • Tan A., Bieber A.K., Stein J.A., Pomeranz M.K. Diagnosis and management of vulvar cancer: A review. J Am Acad Dermatol. 2019; 81(6): 1387-96. https://doi.org/10.1016/j.jaad.2019.07.055.
  • Pushkarev V.A., Men'shikov K.V., Sharifgaliev I.A., Pushkarev A.V., Mukhametdinov M.R. Vozmozhnosti khirurgicheskogo lecheniya mestnorasprostranennogo raka vul'vy. Obzor literatury i klinicheskoe nablyudenie. Onkoginekologiya. 2023; 1: 54-63.
  • Zolotorevskaya O.S., Grishchenko E.V., Elgina S.I., Rudaeva E.V., Mozes K.B., Mozes V.G. Klinicheskii sluchai raka vul'vy. Meditsina v Kuzbasse. 2022; 21(4): 92-95.
  • Mitin T.V., Den'gina N.V. Kratkie metodicheskie rekomendatsii po luchevoi terapii raka vul'vy. 2018.
  • Alkatout I., Schubert M., Garbrecht N., Weigel M.T., Jonat W., Mundhenke C., Günther V. Vulvar cancer: epidemiology, clinical presentation, and management options. Int J Womens Health. 2015; 7: 305-13. https://doi.org/10.2147/IJWH.S68979.
  • Zharov A.V., Novikova E.G., Rerberg A.G., Kolesnikova E.V. Innovatsionnye podkhody k lecheniyu bol'nykh s mestnymi retsidivami raka vul'vy na fone skleroticheskogo lishaya. Opukholi zhenskoi reproduktivnoi sistemy. 2022; 18(4): 59-68. https://doi.org/10.17650/1994-4098-2022-18-4-59-68.
  • Campaner A.B., Cardoso F.A., Fernandes G.L., Veasey J.V. Verrucous carcinoma of the vulva: diagnosis and treatment. An Bras Dermatol. 2017; 92(2): 243-5. https://doi.org/10.1590/abd1806-4841.20174929.
  • Singh N., Gilks C.B. Vulval squamous cell carcinoma and its precursors. Histopathology. 2020; 76(1): 128-38. https://doi.org/10.1111/his.13989.
  • Hinten F., Molijn A., Eckhardt L., Massuger L.F.A.G., Quint W., Bult P., Bulten J., Melchers W.J.G., de Hullu J.A. Vulvar cancer: Two pathways with different localization and prognosis. Gynecol Oncol. 2018; 149(2): 310-7. https://doi.org/10.1016/j.ygyno.2018.03.003.
  • Woelber L., Bommert M., Prieske K., Fischer I., Zu Eulenburg C., Vettorazzi E., Harter P., Jueckstock J., Hilpert F., de Gregorio N., Iborra S., Sehouli J., Ignatov A., Hillemanns P., Fuerst S., Strauss H.G., Baumann K., Beckmann M., Mustea A., Meier W., Wimberger P., Hanker L., Canzler U., Fehm T., Luyten A., Hellriegel M., Kosse J., Heiss C., Hantschmann P., Mallmann P., Tanner B., Pfisterer J., Mahner S., Schmalfeldt B., Jaeger A. Pelvic Lymphadenectomy in Vulvar Cancer - Does it make sense? Geburtshilfe Frauenheilkd. 2020; 80(12): 1221-8. https://doi.org/10.1055/a-1120-0138.
  • Olawaiye A.B., Cuello M.A., Rogers L.J. Cancer of the vulva: 2021 update. Int J Gynaecol Obstet. 2021; 155s1 (s1): 7-18. https://doi.org/10.1002/ijgo.
  • Vulvar-cancer. Statistics [Internet]. [cited 2024 Feb 1]. https://www.cancer.net/cancer-types/vulvar-cancer/statistics.
  • Krikunova L.I., Mkrtchyan L.S., Kaplan M.A., Rykova E.V., Kapinus V.N. Vozmozhnosti fotodinamicheskoi terapii raka vul'vy. Radiatsiya i risk. 2015; 24(2): 107-15.
  • Gaffney D.K., King B., Viswanathan A.N., Barkati M., Beriwal S., Eifel P., Erickson B., Fyles A., Goulart J., Harkenrider M., Jhingran A., Klopp A., Koh W.J., Lim K., Petersen I., Portelance L., Small W. Jr., Stewart A., Wiebe E., Wolfson A., Yashar C., Bosch W. Consensus Recommendations for Radiation Therapy Contouring and Treatment of Vulvar Carcinoma. Int J Radiat Oncol Biol Phys. 2016; 95(4): 1191-200. https://doi.org/10.1016/j.ijrobp.2016.02.043.
  • van der Velden J., Fons G., Lawrie T.A. Primary groin irradiation versus primary groin surgery for early vulvar cancer. Cochrane Database Syst Rev. 2011. https://doi.org/10.1002/14651858.CD002224.pub2.
  • Ashrafyan L.A., Antonova I.B., Berlev I.V., Verenikina E.V., Grinevich V.N., Demidova L.V., Kolomiets L.A., Kravets O.A., Kreinina Yu.M., Kuznetsov V.V., Mukhtarullina S.V., Novikova E.G., Snegovoi A.V., Tyulyandina A.S., Shevchuk A.S., Ul'rikh E.A. Klinicheskie rekomendatsii Ministerstva zdravookhraneniya RF. Rak vul'vy. 2020.
  • Wright J.L., Yom S.S., Awan M.J., Dawes S., Fischer-Valuck B., Kudner R., Mailhot Vega R., Rodrigues G. Standardizing Normal Tissue Contouring for Radiation Therapy Treatment Planning: An ASTRO Consensus Paper. Pract Radiat Oncol. 2019; 9(2): 65-72. https://doi.org/10.1016/j.prro.2018.12.003.
  • Rishi A., Rollins M., Ahmed K.A., Hunt D.C., Sarkar P., Fernandez D.C., Hoffman M.S., Apte S.M., Shahzad M.M.K., Chon H.S., Chern J.Y., Wenham R.M., Montejo M.E. High-dose intensity-modulated chemoradiotherapy in vulvar squamous cell carcinoma: Outcome and toxicity. Gynecol Oncol. 2020; 156(2): 349-56. https://doi.org/10.1016/j.ygyno.2019.11.027.
  • Kachnic L.A., Winter K., Myerson R.J., Goodyear M.D., Willins J., Esthappan J., Haddock M.G., Rotman M., Parikh P.J., Safran H., Willett C.G. RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal. Int J Radiat Oncol Biol Phys. 2013; 86(1): 27-33. https://doi.org/10.1016/j.ijrobp.2012.09.023.
  • Rao Y.J., Chundury A., Schwarz J.K., Hassanzadeh C., DeWees T., Mullen D., Powell M.A., Mutch D.G., Grigsby P.W. Intensity modulated radiation therapy for squamous cell carcinoma of the vulva: Treatment technique and outcomes. Adv Radiat Oncol. 2017; 2(2): 148-58. https://doi.org/10.1016/j.adro.2017.02.006.
  • Abuhijla F., Salah S., Al-Hussaini M., Mohamed I., Jaradat I., Dayyat A., Almasri H., Allozi A., Arjan A., Almousa A., Abu-Hijlih R. Factors influencing the use of adaptive radiation therapy in vulvar carcinoma. Rep Pract Oncol Radiother. 2020; 25(5): 709-13. https://doi.org/10.1016/j.rpor.2020.06.005.
  • Kortekaas K.E., van de Vijver K.K., van Poelgeest M.I.E., Gilks C.B., Smit V.T.H.B.M., Arif S., Arora D., Faruqi A., Ganesan R., Griffin N.R., Hale R., Hock Y.E., Horn L.C., McCluggage W.G., Mukonoweshuro P., Park K.J., Rous B., Tanchel B., Van Rompuy A.S., van Schalkwyk G., Vella J., Vergine M., Singh N., Bosse T. Practical Guidance for Measuring and Reporting Surgical Margins in Vulvar Cancer. Int J Gynecol Pathol. 2020; 39(5): 420-7. https://doi.org/10.1097/PGP.0000000000000631.
  • Nooij L.S., van der Slot M.A., Dekkers O.M., Stijnen T., Gaarenstroom K.N., Creutzberg C.L., Smit V.T., Bosse T., van Poelgeest M.I. Tumour-free margins in vulvar squamous cell carcinoma: Does distance really matter? Eur J Cancer. 2016; 65: 139-49. https://doi.org/10.1016/j.ejca.2016.07.006.
  • Yang J., Delara R., Ghaith S., Newman H., Magrina J., Butler K., Kumar A., Dinh T., Chen L., Magtibay P. Tumor-free margins and local recurrence in squamous cell carcinoma of the vulva. Gynecol Oncol. 2020; 158(3): 555-61. https://doi.org/10.1016/j.ygyno.2020.06.503.
  • Te Grootenhuis N.C., Pouwer A.W., de Bock G.H., Hollema H., Bulten J., van der Zee A.G.J., de Hullu J.A., Oonk M.H.M. Margin status revisited in vulvar squamous cell carcinoma. Gynecol Oncol. 2019; 154(2): 266-75. https://doi.org/10.1016/j.ygyno.2019.05.010.
  • Oonk M.H.M., Slomovitz B., Baldwin P.J.W., van Doorn H.C., van der Velden J., de Hullu J.A., Gaarenstroom K.N., Slangen B.F.M., Vergote I., Brännström M., van Dorst E.B.L., van Driel W.J., Hermans R.H., Nunns D., Widschwendter M., Nugent D., Holland C.M., Sharma A., DiSilvestro P.A., Mannel R., Boll D., Cibula D., Covens A., Provencher D., Runnebaum I.B., Luesley D., Ellis P., Duncan T.J., Tjiong M.Y., Cruickshank D.J., Kjølhede P., Levenback C.F., Bouda J., Kieser K.E., Palle C., Spirtos N.M., O’Malley D.M., Leitao M.M., Geller M.A., Dhar K., Asher V., Tamussino K., Tobias D.H., Borgfeldt C., Lea J.S., Bailey J., Lood M., Eyjolfsdottir B., Attard-Montalto S., Tewari K.S., Manchanda R., Jensen P.T., Persson P., van Le L., Putter H., de Bock G.H., Monk B.J., Creutzberg C.L., van der Zee A.G.J. Radiotherapy Versus Inguinofemoral Lymphadenectomy as Treatment for Vulvar Cancer Patients With Micrometastases in the Sentinel Node: Results of GROINSS-V II. J Clin Oncol. 2021; 39(32): 3623-32. https://doi.org/10.1200/JCO.21.00006.
  • Gien L.T., Slomovitz B., van der Zee A., Oonk M. Phase II activity trial of high-dose radiation and chemosensitization in patients with macrometastatic lymph node spread after sentinel node biopsy in vulvar cancer: GROningen INternational Study on Sentinel nodes in Vulvar cancer III (GROINSS-V III/NRG-GY024). Int J Gynecol Cancer. 2023; 33(4): 619-22. https://doi.org/10.1136/ijgc-2022-004122.
  • Stecklein S.R., Frumovitz M., Klopp A.H., Gunther J.R., Eifel P.J. Effectiveness of definitive radiotherapy for squamous cell carcinoma of the vulva with gross inguinal lymphadenopathy. Gynecol Oncol. 2018; 148(3): 474-9. https://doi.org/10.1016/j.ygyno.2018.01.007.
  • Ashmore S., Crafton S.M., Miller E.M., Krivak T.C., Glaser S.M., Teterichko S.R., Sukumvanich P., Viswanathan A.N., Beriwal S., Horne Z.D. Optimal overall treatment time for adjuvant therapy for women with completely resected, node-positive vulvar cancer. Gynecol Oncol. 2021; 161(1): 63-9. https://doi.org/10.1016/j.ygyno.2021.01.003.
  • Gill B.S., Bernard M.E., Lin J.F., Balasubramani G.K., Rajagopalan M.S., Sukumvanich P., Krivak T.C., Olawaiye A.B., Kelley J.L., Beriwal S. Impact of adjuvant chemotherapy with radiation for node-positive vulvar cancer: A National Cancer Data Base (NCDB) analysis. Gynecol Oncol. 2015; 137(3): 365-72. https://doi.org/10.1016/j.ygyno.2015.03.056.
  • Beriwal S., Shukla G., Shinde A., Heron D.E., Kelley J.L., Edwards R.P., Sukumvanich P., Richards S., Olawaiye A.B., Krivak T.C. Preoperative intensity modulated radiation therapy and chemotherapy for locally advanced vulvar carcinoma: analysis of pattern of relapse. Int J Radiat Oncol Biol Phys. 2013; 85(5): 1269-74. https://doi.org/10.1016/j.ijrobp.2012.11.012.
  • Kim C.H., Olson A.C., Kim H., Beriwal S. Contouring inguinal and femoral nodes; how much margin is needed around the vessels? Pract Radiat Oncol. 2012; 2(4): 274-8. https://doi.org/10.1016/j.prro.2011.12.005.
  • Moore D.H., Ali S., Koh W.J., Michael H., Barnes M.N., McCourt C.K., Homesley H.D., Walker J.L. A phase II trial of radiation therapy and weekly cisplatin chemotherapy for the treatment of locallyadvanced squamous cell carcinoma of the vulva: a gynecologic oncology group study. Gynecol Oncol. 2012; 124(3): 529-33. https://doi.org/10.1016/j.ygyno.2011.11.003.
  • Lei L., Tan L., Zhao X., Zeng F., Xu D. A prognostic nomogram based on lymph node ratio for postoperative vulvar squamous cell carcinoma from the Surveillance, Epidemiology, and End Results database: a retrospective cohort study. Ann Transl Med. 2020; 8(21): 1382. https://doi.org/10.21037/atm-20-3240.
  • Gerszten K., Selvaraj R.N., Kelley J., Faul C. Preoperative chemoradiation for locally advanced carcinoma of the vulva. Gynecol Oncol. 2005; 99(3): 640-4. https://doi.org/10.1016/j.ygyno.2005.07.126.
  • Natesan D., Hong J.C., Foote J., Sosa J.A., Havrilesky L., Chino J. Primary Versus Preoperative Radiation for Locally Advanced Vulvar Cancer. Int J Gynecol Cancer. 2017; 27(4): 794-804. https://doi.org/10.1097/IGC.0000000000000938.
  • Cordoba S., Cordoba A., Gil B., Benlloch R., Rodriguez S., NajjariJamal D., Santana S., Bresson L., de la Fuente C., Romero J. Is There a Place for Brachytherapy in Vulvar Cancer? A Narrative Review. Cancers (Basel). 2023; 15(23): 5581. https://doi.org/10.3390/cancers15235581.
  • Mahantshetty U., Krishnatry R., Hande V., Jamema S., Ghadi Y., Engineer R., Chopra S., Gurram L., Deshpande D., Shrviastava S. Magnetic Resonance Image Guided Adaptive Brachytherapy in Locally Advanced Cervical Cancer: An Experience From a Tertiary Cancer Center in a Low and Middle Income Countries Setting. Int J Radiat Oncol Biol Phys. 2017; 99(3): 608-17. https://doi.org/10.1016/j.ijrobp.2017.06.010.
  • Hughes K.E., McLaughlin C.M., Fields E.C. High-Dose Rate Salvage Interstitial Brachytherapy: A Case-Based Guide to the Treatment of Therapeutically Challenging Recurrent Vulvar Cancer. Front Oncol. 2017; 7: 224. https://doi.org/10.3389/fonc.2017.00224.
  • Yaney A., Healy E., Pan X., Martin D., Quick A. Clinical outcomes of distal vaginal and vulvar cancer treated with image-guided brachytherapy. J Contemp Brachytherapy. 2021; 13(4): 419-25. https://doi.org/10.5114/jcb.2021.108596.
  • Castelnau-Marchand P., Escande A., Mazeron R., Bentivegna E., Cavalcanti A., Gouy S., Baratiny C., Maroun P., Morice P., Haie-Meder C., Chargari C. Brachytherapy as part of the conservative treatment for primary and recurrent vulvar carcinoma. Brachytherapy. 2017; 16(3): 518-25. https://doi.org/10.1016/j.brachy.2017.01.005.
  • Kellas-Sleczka S., Bialas B., Fijalkowski M., Wojcieszek P., Szlag M., Cholewka A., Ślęczka M., Kołosza Z. Interstitial high-dose-rate brachytherapy in locally advanced and recurrent vulvar cancer. J Contemp Brachytherapy. 2016; 8(1): 32-40. https://doi.org/10.5114/jcb.2016.58081.
  • Dyk P.T., Richardson S., Badiyan S.N., Schwarz J.K., Esthappan J., Garcia-Ramirez J.L., Grigsby P.W. Outpatient-based high-dose-rate interstitial brachytherapy for gynecologic malignancies. Brachytherapy. 2015; 14(2): 231-7. https://doi.org/10.1016/j.brachy.2014.11.017.
Еще
Статья обзорная
QR-код для установки приложения SciUp Наведите камеру и скачайте бесплатное приложение SciUp