The design of optical sensor element for microfluidic chips based on the borosilicate porous glasses

Автор: Evstrapov A.A., Esikova N.A., Rudnitskaya G.E., Antropova T.V., Anfimova I.N.

Журнал: Научное приборостроение @nauchnoe-priborostroenie

Рубрика: Исследования, приборы, методики

Статья в выпуске: 1 т.20, 2010 года.

Бесплатный доступ

The work on chemical protein immobilization on the borosilicate porous glass was presented. Transmittance and fluorescence spectra of porous glasses at different stages of protein immobilization and after immune reaction have been measured. Images of porous glass surface were received by scanning near-field optical microscopy. The influence of drying regime between surface activation and silanization stages has been studied. The influence of silanization on protein immobilization was compared with the use of toluene and acetone. It was shown that the immune reaction results in the change of glass optical characteristics. The principal opportunity of the microsensor element production on the base of borosilicate porous glass was presented.

Еще

Porous glass, sensor element, laser scanning confocal microscopy, scanning near field optical microscopy, optical spectrometry

Короткий адрес: https://sciup.org/14264641

IDR: 14264641

Статья научная