Software package for determination of metabolite concentrations in brain tissue of several volunteers using magnetic resonance spectroscopy

A "Magnetom Vision" tomograph was used to obtain in vivo magnetic resonance spectra of white brain matter from a group of 16 healthy volunteers 19 to 60 years old. The paper presents a software package for processing these spectra with minimal systematic errors and estimation of confidence levels. For the group tested the mean molar metabolite concentrations (mmol / L) of white brain matter were 10.70 ± 1.25 (N-acetyl-aspartate C(NAA)); 6.53 ± 0.67 (phosphocreatine C(PCr)); 1.67 ± 0.35 (choline C(Cho)); 6.39 ± 1.54 (myo inositol C(Ins)).