Response of the heart pumping function in laboratory animals to the introduction of adrenoblockers

For the first time, the reaction of the stroke volume of blood was studied when в, а1 and а2-blockers were administered to animals subjected to various modes of motor activity. It was revealed that in all the studied experimental groups of animals in the first week there is a decrease in the response of SV to the introduction of в, а1 and an increase in the response of SV to the administration of а2-blocker. At the same time, the most pronounced decrease in the SV response to the administration of different subtypes of adrenergic blockers is observed in the group of animals with limited motor activity, and the smallest decrease in the SV response is observed in the group of animal’s subject to enhanced motor mode. It has been established that the mode of limited motor activity, i.e. hypokinesia causes a more pronounced reaction of heart rate to the introduction of в and а1-blockers and a less pronounced reaction to the introduction of а2-adrenergic blocker. The regime of systematic muscle training, on the contrary, contributes to a less pronounced response of heart rate to the introduction of в and а1 -adrenergic blockers and a more pronounced response to the administration of a2-adrenergic blocker.