Surgical reconstruction of fractured cervical vertebrae with osteosubstitution materials

Objectives: to evaluate the clinical efficiency and safety of the of coral-based trabecular hydroxyapatite osteosubstitution material in vertebral fractures of cervical spine.Materials and methods: The study represents the results of surgical treatment of 89 patients with fractures of cervical spine vertebrae with the use of coral- based bone substitute material “Bonemedik”, performed between 2010 and 2016. Mean observation time was from 1.4 up to 7.3 years. During the surgery, after decompression of spinal cord, bony defect has been filled with bone substitute material, and then bones have been fixated with metal plate. Computer tomography was used to evaluate osseointegration and biodegradation, bone density was measured in Hounsfield units.Results: In every case we have observed tight donor-recipient bone contact. Bone density in contact zone matched the criteria of marked osseointegration (difference between density in contact zone and appropriate zone of adjacent vertebrae was 2-9%), there were no zones of clarification between bone and substitute material.Conclusion: Coral-based material «Bonemedik» is an effective and safe material for replacement of bone tissue defects during surgical intervention in cervical spine.