Outcomes of application the enhanced recovery protocol for perforated duodenal ulcer

Objective: Improvement of the results of treatment of patients operated on for perforated duodenal ulcer (PDU) with the use of the Enhanced Recovery Protocol (ERP).Material and methods. The results of surgical treatment of 102 patients with PDU in the period 2015-2019 were analyzed. A monocenter prospective randomized study was performed at the clinical base of the Department of surgery and endoscopy of the Pirogov Russian National Research Medical University. The operated patients were divided into 2 groups: the main group (fast-track group (FT-group), with ERP) and the control group (CG, standard perioperative management). The severity of postoperative complications was assessed according to the Clavien-Dindo scale.Results. In the FT-group, the duration of the operation was 78.96±4.51 minutes. In the FT-group, 3 postoperative complications were identified. The duration of hospitalization is 3.85±0.14 days. In CG, the duration of the operation was 114.32±8.73 minutes. 10 postoperative complications were identified in the CG. The duration of hospitalization is 6.84±0.29 days. There were no deaths or repeated hospitalizations in both groups.Conclusion. The use of ERP can improve the immediate results of surgical treatment of patients with PDU and reduce the length of hospital stay.