Risk of reproductive system pathology in women-colourers contacting with aromatics hydrocarbons

Genetic polymorphism of xenobiotics’ metabolism enzymes is the most important factor determining individual sensibility of organism to harmful chemical substances of production environment. This factor generates the predisposition to occupational pathology. The performed studies have indicated that maximum risk for reproductive system pathology in women-colourers, contacting with aromatics hydrocarbons, is stipulated by the absence of the activity of the enzymes of glutathione-transferase Т1 and glutathione-transferase М1 encoded by genes (genotype GSTM1«0»/GSTT1«0»).