Role of cylin-dependent kinases 2,4,6 in the process of repair of insulocytes of the islandsof langerhans of the pancreatic gland

Cyclin-dependent kinases (CDKs) are a family of protein serine / threonine kinases whose activity depends on interaction with a non-catalytic regulatory subunit called cyclin. CDKs play an important role in cell cycle mechanisms responsible for coordinating cell growth, DNA replication, and mitosis which makes them necessary for proliferation [22]. This article reviews current information on the role of cyclin-dependent kinases in the repair of b-cells pancreatic islet of lang-erhans.