Роль е-кадгерина и b-катенина при плоскоклеточном раке органов головы и шеи

Роль е-кадгерина и b-катенина при плоскоклеточном раке органов головы и шеи

Автор: Петрова А.А., Самойлова С.И., Магомедкеримова Л.В., Партс С.А., Решетов И.В.

Журнал: Сибирский онкологический журнал @siboncoj

Рубрика: Обзоры

Статья в выпуске: 6 т.22, 2023 года.

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Цель исследования - представить и обобщить имеющиеся в современной литературе данные о прогностическом значении маркеров E-кадгерина и β-катенина для плоскоклеточного рака органов головы и шеи, обосновать потенциальную пользу внедрения исследований данной области в клиническую практику в рамках персонализированного подхода к лечению плоскоклеточного рака органов головы и шеи. Материал и методы. выполнен поиск и обзор литературы в базах данных Pubmed, Scopus, Google Scholar и РИНЦ на предмет связи уровня данных маркеров с прогнозом и клинической картиной заболевания, а также агрессивностью поведения опухоли и ответом на лечение.

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Е-кадгерин, β-катенин, плоскоклеточный рак, карцинома, эпителиально-мезенхимальный переход, прогноз, органы головы и шеи

Короткий адрес: https://sciup.org/140303550

IDR: 140303550   |   DOI: 10.21294/1814-4861-2023-22-6-130-137

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