Role of peroxide lipids oxidation in formation of hemodynamic disturbances on the background of chronic cobalt intoxication in experiment at rats

Free-radical processes proceed in all organs and tissues, being normal metabolic reaction which is impor-tant for a regulation of substances transport through membranes of prostaglandinum, leucotriens synthe-sis, exchange of steroid hormones and catecholamins. Disturbance of free-radical oxidation is considered as the early, universal and nonspecific mechanism of damage of stationary rate the early, universal and nonspecific mechanism of damage, underlying in the basis of various diseases.