Protein C role in microcirculation disturbance in patients with gingivitis

The research purpose is focused on studying the role of protein C system in coagulation component disturbance of hemostasis and fibrinolysis system in patients with different forms of gingivitis. The decrease of protein C and antithrombin lll activity, the decrease of plasminogen reserve in blood, thrombin time shortening and the resistance of factor Va Via to protein C are watched in patients with different forms of gingivitis. The most marked changes in protein C system may be observed in exacerbation phase of acute and chronic ulcerative generalized gingivitis and chronic catarrhal generalized gingivitis. The reduction of indices of protein C system doesn't occur in remission phase except in patients with chronic catarrhal ulcerative generalized gingivitis.