Serotonin impact on fertility rate on D. gyrociliatus model

The paper considers the effect of increased and decreased serotonin levels, as well as reduced serotonylation levels on the development of D.gyrociliatus. Two series of experiments were conducted. In the first series of experiments, freshly laid clutches were divided into 4 groups, to which serotonin precursor (10-6M), parachlophenylalanine (10-6M), cystamine (10-6M) and control were added. In the second series of experiments, adult females aged 40 days were incubated in solutions of serotonin precursor, parachlorophenylalanine, cystamine and control, then fresh clutches were obtained. In the first series of experiments, embryos incubated in the serotonin precursor hatched on the 7th day of development, as well as the control group. Individuals incubated in cystamine hatched on the 7-8 day of development. Individuals incubated in parachlorophenylalanine hatched on the 10th-13th day of development, with the lowest percentage of hatches. In the second series of experiments, a similar pattern was observed: the control group, as well as embryos obtained from mothers incubated in serotonin precursor hatched on day 7 of development, whereas embryos obtained from mothers incubated in parachlorophenylalanine and cystamine hatched much later. The results obtained demonstrate that serotonin affects the development of embryos, in addition, they show that the level of maternal serotonin also affects the development of embryos. The results are consistent with the previously obtained data.