Sexual activity and Alzheimer's disease: neuroendocrine rehabilitation tools and technologies

Alzheimer's disease is evolutionary, genetic and epigenetic routing Homo sapiens , with the introduction of the ADNM-365/22/77 (Alzheimer’s disease & nuclear medicine (ADNM) rehabilitation program and medical and social neurocompunctions and accompaniments. Gerontology and geriatrics, gynecology / andrology and neuroendocrinology, neurophysiology and neurosociology route H. sapiens to active / healthy / qualitative / religious / moral / sexual / neurocompunctive Longevity . The huge increase in scientific data obtained both in preclinical and clinical studies is closing a large gap in knowledge about the sex-specific features of the course of many diseases (neurodegenerative, mental, autoimmune, oncological, cardiovascular, infectious). However, the factors that determine gender differences in epidemiology, pathophysiology, clinical picture, and outcomes of a number of pathologies remain unexplored. This literature review provides an analysis of current research on the role of hormonal regulation in gender medicine and gender differences in key clinical areas. Sex differences in immune response, cardiovascular disease, neurological disorders, COVID-19 are described in this article. It is shown that at present all the prerequisites for the formation of personalized approaches in clinical medicine and public health to improve the quality of life of patients and the health of the population as a whole are ripe.