Synthesis of 1- (3-benzoylbenzyl) uracil derivatives as potential antiviral agents

Автор: Novikov M.S., Lysenko K.N., Heisman A.N., Ozerov A.A.

Журнал: Волгоградский научно-медицинский журнал @bulletin-volgmed

Рубрика: Фармакология токсикология

Статья в выпуске: 4 (28), 2010 года.

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Condensation of equimolar quantity of 2,4-bis(trimethylsilyloxy)pyrimidines and 3-(benzoyl)benzylbromides led to 1-(3-benzoylbenzyl)uracils, bearing various substituents at 5 position of uracil heterocycle. The yield of target compounds amounted to 56-69 %. These compounds are potential anti-HIV-1 agents.

Synthesis, uracil, 4-bis(trimethylsilyloxy)pyrimidines, potential antiviral agents

Короткий адрес: https://sciup.org/142148858

IDR: 142148858

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