Synthesis of acetanylides - 2-thio-6-phenyluracil derivatives as potential anti-HIV-1 agents

Автор: Ozerov A.A., Novikov M.S., Solodunova G.N., Paramonova M.P.

Журнал: Волгоградский научно-медицинский журнал @bulletin-volgmed

Рубрика: Фармакология токсикология

Статья в выпуске: 4 (28), 2010 года.

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Treatment of 6-phenyl-2-thiouracil with chloro acetanilydes containing various substitutes in aromatic cycle led to 2-[(1,6-dihydro-6-oxo-4-phenyl-2-pyrimidinyl)thio]-N-phenylacetamides with a 35-81 % yield. These compounds are potential anti-HIV-1 agents.

Synthesis, 2-thiouracil, s-алкилирование, s-alkylation, potential antiviral agents

Короткий адрес: https://sciup.org/142148857

IDR: 142148857

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