Synthesis and psychopharmacological properties of 3-(2-oxopropyl) quinazolin-4 (3 H) hydrazone

3-(2-oxopropyl)quinazolin-4(3H)-on hydrazone was synthesized by alkylation of quinazolin-4(3H)-on with chloroacetone followed by the condensation with hydrazine. The compound enhanced the hypnotic effect of sodium thiopental and reduced the convulsive effect of picrotoxin.