Synthesis of the novel acetanilide nucleic acid bases derivatives
Автор: Merezhkina D.V., Kozlov S. Yu., Pluzhnikova A.R., Tuzhikova M.O., Novikov M.S., Ozerov A.A.
Журнал: Волгоградский научно-медицинский журнал @bulletin-volgmed
Статья в выпуске: 1 (69), 2021 года.
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N-alkylation of nucleic bases and 5-(phenylamino)uracil with 3,5-dimethylchloroacetanilide readily proceeds in anhydrous DMF medium in the presence of potassium carbonate at room temperature. 5-(Phenylamino)uracil gives predominantly N1,N3-disubstituted alkylation product, unlike other substrates used.
Uracil, thymine, cytosine, adenine, 5-(phenylamino)uracil, chloroacetanilide
Короткий адрес: https://sciup.org/142229370
IDR: 142229370
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