Systemic therapy for anaplastic thyroid cancer: a literature review

Background. Anaplastic thyroid cancer is a rare but aggressive disease with an extremely low survival rate. Improved diagnostic and therapeutic options have enabled the development of a multidisciplinary approach (surgery + radiation therapy + systemic antitumor therapy options) that has improved overall survival, highlighting the importance of a multidisciplinary approach. However, despite the widespread use of chemotherapy, targeted therapy and immunotherapy, patient outcomes remain disappointing.