Perioperative risk reduction for vertebrologic surgeries in patients with hereditary diseases of the connective tissue

Design of the Study. A retrospective analysis of a series of clinical cases. Purpose. To evaluate the functional state of internal organs for hereditary diseases of the connective tissue, as well as the reduction of perioperative risk in order to achieve maximum impact of vertebrologic correction. Object. 22 patients at the age from nine (9) months to 24 years with the connective tissue hereditary diseases who underwent surgeries for decompensated deformities of the spine analyzed within the period of 2011-2014. Methods. The analysis of functional state was made for the main selected syndromes: the syndrome of neurological disorders; asthenic syndrome; valve syndrome; thoracic outlet syndrome; arrhythmia syndrome; bronchopulmonary syndrome; visceral syndrome; the syndrome of vision organ pathology; hypermobility syndrome; vertebrogenic syndrome; cosmetic syndrome. We used clinical, functional, and statistical methods. The presence of developmental anomalies and functional disorders of the heart, respiratory organs, gastrointestinal tract, homeostasis and kidneys served as the subject of the analysis. Results. The main pathological states highlighted which characterize changes in various organs and systems for hereditary diseases of the connective tissue and determine both the risk of surgical correction and anesthesia providing, and the postoperative course. Both the plan of the patient multidisciplinary observation and the surgical tactics of systemic spine deformity correction substantiated. Discussion. To represent the direct connection of functional state with the risk of anesthesia providing and surgical treatment. Conclusion. The analysis of the individual profile of somatic pathology in each nosologic group allows objectifying the risk in view of somatic, neurological state and the extent of intervention.