Sleep and COVID-19: neurophysiological and biochemical issues

Functional disorders of the nervous system against the background of Covid-19 are reviewed with the emphasis on sleep and circadian clock disorders during the pandemic. The pandemic is regarded as the strong stress factor that affects sleep and the clock. A large risk group consists of elderly people and people with concomitant somatic pathology. Data on the effect of SARS-CoV-2 on other organs and systems, on the functioning of the immune system, are presented.