Specificity of the development of acute coronary syndrome/acute myocardial infarction in men of various ages in one of the districts of Tashkent (according to the data of registry)

Analysis of the ratio of times of the patients hospitalization (analysis included 262 hospitalized patients) from the moment of beginning of the pain attack showed that only 32 (12.2% of the total number of hospitalized patients) men admitted during first 2 hours, of them only 5(1.9%) patients were presented into the hospital during “the golden first hour” when it was possible to achieve maximum effect of antithrombotic therapy. During the first 2 hours from the moment of the pain appearance the pain in the chest of the age group of 40-49 years the frequency of referral into the medical services accounted for 14.3%. The men frequently addressed for medical aid during the first 3 hours in the age group 60-69 years (16.9%). The special attention was given to the very high percent of patients admitted very late, more than on a day after appearance of pains (38.2%).

We also analyzed morbidity due to AMI. During period of observation the parameter of morbidity rate was 424.3 cases per 100.000 of population of the appropriate age cohort. Analysis of morbidity in relation to age revealed the following picture: among the men at the age 20-29 years – 16.3 cases; 30-39 years – 88.9; 40-49 – 335.6; 50-59 years – 960.2 and at the age 60-69 years – 2574.3 cases per 100.000 of population of the corresponding age category. The velocity of increase rate in groups of 30-39 years in men in relation to previous age interval accounted 5.45; in group of 40-49 years old -3.8; in group 50-59 years -2.86; and at the age of 60-69 – 2.68. According to our data the mortality rate because of AMI per 100.000 of population over the studied period accounted for 350.6 cases. Analysis of the mortality rate with regard to age revealed the followings: among the men of the age 20-29 years – 16.3 cases; of 30-39 years – 69.1; of 40-49 years old – 262.3; 50-59 – 826.6 and of the age of 60-69 years – 2102.9 cases per 100.000 of population of the corresponding age category.

Thus, under suspicion of development of acute coronary pathology during the first 2 hours only 1/10 of patient has been hospitalized, and during the first hour – not more than 1.9% of the patients, that may explain the high specific weight of the prehospital lethality – 43.5%. The morbidity rate due to acute myocardial infarction in the district of Tashkent at the age of 2069 years was 424.3 cases per 100.000 of adult population, and its grow increased with increase in age. The mortality rate because of AMI accounted for 350.6 cases per 100.000 of population. The most distribution rate of ACS/AMI was found at the age group 6064 years old (24.1%).