A method of treating patients with high-risk progression localized prostate cancer

A combination of brachytherapy and distance X-ray therapy is a suitable method for treating patients with a high risk of prostate cancer progression. This can help to yield better results, in comparison with radical prostatectomy and distance X-ray therapy alone. However, application of a complex X-ray therapy has considerable disadvantages. This paper contains a description of a method of treatment of localized prostate cancer, which includes intraprostatic and paraprostatic administration of 5-fluorouracil (radiomodifier and chemotherapeutic agent), followed by complex X-ray therapy (brachytherapy and distance X-ray therapy). A clinical case of successful treatment of a patient with high-risk prostate cancer using the proposed method is described. The proposed method of therapy for patients with localized prostate cancer, who have a high risk of progression of the disease, provides the improvement of the nearest and long-term results of treatment and helps to decrease the probability of prostate cancer recurrence and, therefore, avoid the expenses for specialized antitumor methods of treatment. The method helps to prevent a series of side effects of X-ray treatment, such as prostatitis, cystitis, urethritis and rectitis. Consequently, this reduces the duration of rehabilitation of such patients and helps to avoid the expenses for symptomatic treatment.