Способы и средства медикаментозной профилактики суицидов

Автор: Козлов В.А., Голенков А.В., Булыгина И.Е.

Статья в выпуске: 2 (51) т.14, 2023 года.

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Несмотря на то, что суициды потенциально предотвратимы, профилактика суицидов, смертность от которых сравнима со смертностью от бактериальных эпидемий, остаётся актуальной общемировой проблемой. ВОЗ описывает самоубийство как «акт преднамеренного убийства», который находится на крайнем конце непрерывного спектра суицидального поведения. Цель исследования - систематизация сведений о способах и средствах медикаментозной профилактики суицидов. Результаты. Рассмотрены вопросы профилактики суицидов. Авторы пришли к выводу о необходимости выявления предикторов суицидального поведения и формирования однородных групп населения: 1) психически больные (подгруппы - в определениях DSM-V); 2) относительно здоровые люди (те, кто не испытывает социального и экономического неблагополучия, клинически выраженных нарушений здоровья и кого нельзя квалифицировать в дефинициях DSM-V) - имеющих высокий риск совершения суицида в будущем, как имеющих постоянный паттерн предикторов суицидального поведения. Такая классификация позволит создать регистр лиц, склонных к совершению суицида и проводить плановую популяционную и клиническую профилактику совершения суицидов в целевых группах. В качестве средств профилактики суицидов рассмотрены методики ограничения доступа к смертоносным средствам и объектам, программы повышения осведомлённости о проблеме суицидов в школах. Особенно подробно проанализированы вопросы использования фармакологических средств с доказанным антисуицидальным эффектом: холекальциферолов, кетамина, клозапина, солей лития, внутривенных нейролептиков длительного действия, электросудорожной терапии. Исходя из рациональных сведений о биологической активности перечисленных фармакологических следует, что шизофреническое и депрессивное расстройства личности коморбидны суицидальности, но патогенетически с суицидальностью не связаны. Сделаны выводы, что для активной эффективной профилактики суицидов необходимо: 1) потенциальных суицидентов квалифицировать в однородные группы; 2) создать контролирующие структуры, в том числе, с применением цифровых вычислительных средств с целью создания регистра лиц, потенциально способных совершить суицид. В частности, таким средством могут быть технологии искусственного интеллекта и анализа больших данных для оперативного отслеживания триггерных запросов в сети интернет и с помощью средств мобильной связи.

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Профилактика, суицид, кетамин, соли литий, клозапин, эбселен, холекальциферол, внутривенные нейролептики пролонгированного действия

Короткий адрес: https://sciup.org/140301922

IDR: 140301922 | DOI: 10.32878/suiciderus.23-14-02(51)-36-58

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