Comparative evaluation of the biochemical blood profile in the presence of bovine leukemia and leuko-brucella infection

This paper describes the results obtained during the comparative evaluation of protein, mineral, carbohydrate, lipid, and purine metabolism parameters in bovine leukemia virus (BLV) carriers and in animals carrying both brucellosis and leukemia virus. 50 blood serum samples were taken from cows with specific antibodies under the leukemia diagnostic study results obtained with the help of immunological diffusion reactions (IDR), indirect immunofluorescence (IIF) and enzyme-linked immunosorbent assay (ELISA). The subsequent serological analysis of the samples, aimed at detecting a range of bacterial infections (brucellosis, chlamidiosis, paratuberculosis, vibriosis, etc.), resulted in the possibility to establish that the BLV carrier state in most animals is associated with a bacterial infection, in particular brucellosis antibodies were detected in 23 out of 50 (46%) samples. Besides, chlamidiosis, paratuberculosis, vibriosis antibodies were found in some samples, but not so frequently. The subsequent evaluation of the metabolic process levels in carriers of BLV and leuko-brucella infection in comparison with the parameters of clinically healthy animals showed some peculiarities in the biochemical blood profile. In particular, a different trajectory in the change of the protein and lipid metabolism parameters could be determined. The difference consisted in a decrease in albumin and cholesterol concentration in animals infected with BLV, while a significant increase in their level was found in animals with leuko-brucella infection.