Comparative characteristics of the quality of life in patients with senile asthenia and history of COVID-19 three and six months after discharge from the hospital

Background. Patients with COVID-19 and senile asthenia syndrome (SA) are characterized by extremely high comorbidity, heterogeneity, atypical course of the disease, and large number of complications. We carried out a comprehensive assessment of the quality of life (QOL) in patients with COVID-19 and SA considering the high prevalence of this category of patients and the absence of such studies.Material and Methods. Group 1 included 37 patients with SA and history of COVID-19 three months after discharge from the hospital. Group 2 included 35 patients with CA and history of COVID-19 six months later. Control group comprised 34 patients with SA aged over 65 years who did not have COVID-19. The assessment of QOL was carried out according to the SF-36 questionnaire.Results. There was a decrease in absolutely all indicators of physical and psychosocial aspects of health three months after discharge from the hospital. There was a more pronounced decrease in the scales of physical functioning (PF), role-physical functioning (RP), general health (GH), and mental health (MH) after six months. There was a lower QOL in female population according to most scales (PF, RP, GH, MH, and role-emotional functioning (RE)) regardless of the time from the moment of discharge from the hospital, and a higher incidence of depression compared to men.Conclusions. All QOL indicators of patients with SA and history of COVID-19 decreased within the first three months after discharge from the hospital. At the same time, after six months, a decrease in physical status was most pronounced, while the indicators of mental sphere reduced only according to the MH scale. At three and six months after discharge, the quality of life in the male population was higher than in the female population according to the same evaluation scales (PF, RP, GH, MH, and RE). The best indicators of pain scale in men were characteristic only for the first group of patients, whereas there was no statistically significant difference according to the social functioning and MH data. There was a higher incidence of depression in the female population, while the prevalence of anxiety was higher at three months after discharge than after six months.