Comparative assessment of lung function abnormalities in postoperative period in surgical treatment of patients with laryngeal and laryngopharyngeal cancers depending on anesthesia method

External respiration functions were studied in 46 laryngeal cancer patients (stage T2-4N0-1M0) who underwent combined modality treatment including chemoradiotherapy and laryngectomy with lymphodissection. The patients were divided into 2 groups. Group I (n=22) were operated on under xenon anesthesia in the ratio Xe:O2=70%:30% and Group II (n=24) received TIVA combined with N2O in oxygen (60%:40%). The values of external respiration function were studied before surgery, on days 3 and 7 after surgery using «Microspiro HJ-601» spirometer (Japan). A statistically significant reduction in rapid exhalation values by 50-55 % related to pronounced obstructive disturbances was observed in patients operated on under nitrous oxide narcosis. In Xe group patients, the reduction of rapid exhalation values by 20-25 % was observed. Differences were not statistically significant. Xenon anesthesia used for laryngeal and laryngopharyngeal cancer patients contributes to early compensation of ventilation disturbances occurred in postoperative period