Comparative analysis of external and external-internal drainage in malignant distal biliary obstruction

Автор: Shabunin A.V., Lebedev S.S., Tavobilov M.M., Chechenin G.M., Grekov D.N., Karpov A.A., Drozdov P.A.

Журнал: Московский хирургический журнал @mossj

Рубрика: Абдоминальная хирургия

Статья в выпуске: 1 (87), 2024 года.

Бесплатный доступ

Introduction. Purpose of the study. To conduct a comparative analysis of external and external-internal biliary drainage for distal malignant biliary obstruction (DMBO).Research methods. At the Botkin Hospital (Moscow) from 2015 to 2019. We conducted a retrospective analysis of the treatment of patients with PADD, the cause of which was ductal adenocarcinoma of the head of the pancreas. The patients were divided into two groups: G1 - external biliary drainage was performed (n=76), G2 - external-internal biliary drainage (n=94). Characteristics of the groups: age G1 62,3±4,3, G2 63,5±3,9 (p=0,057); gender (m/f) G1 37/41, G2 39/55 (p=0,245); ECOG G1 1,3±0,3, G2 1,4±0,2 (p=0,081); total bilirubin G1 236,2±35,2, G2 228,7±28,5 (p=0,132); alkaline phosphatase G1 658±31,1, G2 649±25,8 (p=0,093); AST G1 216±10,3, G2 213±12,5 (0,086); ALT G1 319±12,2, G2 322±11,5 (p=0,101).Results. When comparing immediate results, a statistically lower number of Clavien-Dindo complications was revealed in patients with external-internal bile diversion (22,3 % versus 37,2 % (p = 0,043). A qualitative analysis of complications revealed that cholangitis (6,4 %, versus 18,1 %) and post-manipulation pancreatitis (2,6 %, versus 19,1 %) were more common in the group with external-internal bile diversion with statistical significance of the differences (p =0,024 and p=0,001, respectively). Liver failure (26,9 %, versus 13,8 %) and cholangiostomy dislocation (12,8 %, versus 4,2 %) developed more often in the group of patients with external biliary decompression (p=0,036 and p=0,041, respectively). Complications such as biliary peritonitis (6,4 % versus 7,4 %) and acute cholecystitis (5,1 % versus 5,3 %) occurred in both groups without significant differences (p=0,791 and p=0,955, respectively).Conclusion. External-internal bile diversion is the preferred procedure for DMBO. External bile diversion should be performed according to individual indications.

Еще

Distal malignant biliary obstruction, percutaneous cholangiostomy

Короткий адрес: https://sciup.org/142240462

IDR: 142240462   |   DOI: 10.17238/2072-3180-2024-1-9-14

Статья научная