The comparative analysis of Pappone procedure versus anatomic ablation of ganglionated plexuses in patients with atrial fibrillation

The comparative analysis of two catheter ablation techniques was presented. One hundred ninety two patients with paroxysmal (32%), persistent (33%) and permanent (35%) atrial fibrillation were randomized on two groups on the basis of surgical treatment: anatomic ablation of left atrial ganglionated plexuses (AGP-ablation) or and antral isolation of pulmonary veins by technique C. Pappone. The sinus rhythm preservation was achieved in 82% of patients with paroxysmal, 76% with persistent and 59% with permanent atrial fibrillation after AGP-ablation. Thus, this approach increases probability of sinus rhythm preservation on 33%, reduces arrhythmogenic effects in 8,2 times and necessity of repeated procedures on 13% in comparison with traditional procedure (pulmonary veins isolation).